Extracellular Matrix in Kidney Fibrosis: More Than Just a Scaffold

Renal resistance index—think of more than just the kidney

1. Schneider C. CHMP assessment report for Pandemrix. Common Name: Pandemic influenza vaccine (H1N1) 1 (split virion, inactivated, adjuvanted) A/California/7/2009 (H1N1)v like strain (X-179A). Procedure No. EMEA/H/C/832/PU/17. EMEA/CHMP/619109/2009. 2009. 26-11-2009 2. Kunisaki KM, Janoff EN. Influenza in immunosuppressed populations: a review of infection frequency, morbidity, mortality, and v...

More than just vanilla.

Extracellular volume fraction provides more imformation than fibrosis

Background Extracellular volume fraction (ECV) has been applied to the detection of diffuse myocardial interstitial fibrosis or exudative pathologic changes in various clinical settings, but there is lack of study to date concerning the significance of ECV at the early phase of left ventricular remodeling. We intended to assess myocardial ECV in essential hypertension and to study the implicati...

AMPKβ subunits: more than just a scaffold in the formation of AMPK complex.

AMP-activated protein kinase (AMPK) is a sensor of energy status composed of a catalytic subunit (AMPKα), a scaffolding subunit (AMPKβ) and a regulatory subunit involved in nucleotide binding (AMPKγ). Activation of AMPK results in enhancement of catabolic processes and downregulation of anabolic pathways with the aim to equilibrate the energy status of the cell. The study of the regulation of t...

More than just big ears

To the non-specialist, large ears in elephants used to mean African, small ears, Indian. But to taxonomists African elephants have long posed a more complex puzzle. During the nineteenth century, it was fashionable for wealthy trophy hunters to assign their own names to species they had shot destined for the museums of Europe. At least 18 elephant subspecies were claimed following this fashion....